Regulation of Prenatal Human Retinal Neurosphere Growth and Cell Fate Potential by Retinal Pigment Epithelium and Mash1
نویسندگان
چکیده
منابع مشابه
Histochemical study of retinal photoreceptors development during pre- and postnatal period and their association with retinal pigment epithelium
Objective(s):The aim of this study was to evaluate distribution and changes of glycoconjugates of retinal photoreceptors during both pre- and postnatal development. Materials and Methods: Tissue sections from days 15 to 20 of Wistar rat embryos and 1 to 12 postnatal days of rat newborns including developing eye were prepared for lectinhistochemistry technique. Horseradish peroxidase (HRP)-label...
متن کاملinvestigation of melanogenic factors gene expression in human adult and neonate retinal pigment epithelium cell cultures
retinal pigment epithelium is responsible for maintaining the structural integrity of the retina by an efficient defense against free radicals, photo-oxidative exposure and light energy. for this purpose the main rpe line of defense is melanosomes. melanin content of retinal pigment epithelium cells in adults and neonates reveals remarkable variations. in the current study we compared melanogen...
متن کاملTissue culture of human retinal pigment epithelium.
Adult human retinal pigment epithelium has been enzymatically isolated and established In tissue culture. Primary cultures survived three to six months. Occasionally, cell lines spontaneously evolved from primary cultures. Melanin granules decreased with the age of the culture, became less pigmented but retained some characterstics of melanin-producing cells. Lipofuscin granules are present, bu...
متن کاملThe metabolism of retinal pigment cell epithelium
A study of respiration and glycolysis in vitro of retinal pigment epithelium and retina minus the pigment epithelial layer has indicated metabolic similarities and differences between the two tissues. Aerobic lactic acid production from glucose was one-half in pigment epithelium what it was in retina, and the Pasteur effect operated with approximately the same efficiency in either tissue. Pigme...
متن کاملProtein database, human retinal pigment epithelium.
The retinal pigment epithelium (RPE) is a single cell layer adjacent to the rod and cone photoreceptors that plays key roles in retinal physiology and the biochemistry of vision. RPE cells were isolated from normal adult human donor eyes, subcellular fractions were prepared, and proteins were fractionated by electrophoresis. Following in-gel proteolysis, proteins were identified by peptide sequ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: STEM CELLS
سال: 2008
ISSN: 1066-5099
DOI: 10.1634/stemcells.2008-0300